News
Additional MinitestWritten on 29.06.26 (last change on 29.06.26) by Ana Shikhiashvili Dear all, for the ones, who have missed a minitest due to illness and provided a medical certificate for it, we will offer an additional minitest next Monday (July 6th). The 5th minitest will also take place on the same day as planned. Please note that this additional minitest will cover every… Read more Dear all, for the ones, who have missed a minitest due to illness and provided a medical certificate for it, we will offer an additional minitest next Monday (July 6th). The 5th minitest will also take place on the same day as planned. Please note that this additional minitest will cover every topic since the beginning of the lectures (without any bonus questions). Best, Bioinfo-2-team |
Challenge File UpdateWritten on 19.06.26 by Lisa-Marie Rolli Dear all, please note that we originally uploaded wrong files for the challenge and just updated them now. So, in case you already downloaded the old files please make sure to download the latest version of all files and use this instead. We are sorry for that and hope that it does not cause any… Read more Dear all, please note that we originally uploaded wrong files for the challenge and just updated them now. So, in case you already downloaded the old files please make sure to download the latest version of all files and use this instead. We are sorry for that and hope that it does not cause any issues for you. All the best, the Bioinfo2 Team |
No lecture on Tuesday, 16.06.2026Written on 15.06.26 by Andrea Volkamer Dear all, Please note that there will be no Bioinformatics II lecture tomorrow. We will continue with the course on Thursday at 2:00 PM as scheduled. Best regards, Andrea Volkamer |
Update to: Lecture today in room 1.06Written on 11.06.26 (last change on 18.06.26) by Lisa-Marie Rolli It seems like AG Rahmann changed their plans, so we are actually back to our seminar room on the ground floor! unfortunately, our usual lecture room is occupied today. Therefore, we moved to room 1.06. We are sorry for the short notice. Looking… Read more It seems like AG Rahmann changed their plans, so we are actually back to our seminar room on the ground floor! unfortunately, our usual lecture room is occupied today. Therefore, we moved to room 1.06. We are sorry for the short notice. Looking forward to seeing many of you in the lecture, The Bioinfo2 Team |
Minitest Results & InspectionWritten on 28.04.26 by Ana Shikhiashvili Dear all, the minitests have been graded and you can find the results under your personal status page. The inspection will take place on Wednesday (29.04) during the office hour. Best, The Bioinfo2 Team |
Code SubmissionWritten on 22.04.26 by Lisa-Marie Rolli Dear all, Just a quick reminder regarding code submissions: We know this might be a bit different from what you’re used to in other… Read more Dear all, Just a quick reminder regarding code submissions: We know this might be a bit different from what you’re used to in other courses (such as Programming 2), so we were more lenient when grading your first assignment. From now on, however, we’ll be enforcing this rule more consistently. If you have any problems with the assignments, feel free to use the forum or the office hours to ask for help. Kind regards, The Bioinfo2 Team |
Office HoursWritten on 14.04.26 by Ana Shikhiashvili Hello everyone, we will be offering Office Hour every Wednesday from 14:00 till 16:00 in room 007. The first OH will take place tomorrow (April 15th). See you then!
-The Bioinformatics 2 Team |
First Assignment & TutorialWritten on 09.04.26 by Maximilian Bähr Hello Everyone! We just now uploaded all the files and materials you need to work on the first exercise sheet! For all of you that dont have access to the Gitlab yet: send an email with your Gitlab username to Max. Also the first Tutorial will be next Monday (13.04 at 08:30) in room 007 in the… Read more Hello Everyone! We just now uploaded all the files and materials you need to work on the first exercise sheet! For all of you that dont have access to the Gitlab yet: send an email with your Gitlab username to Max. Also the first Tutorial will be next Monday (13.04 at 08:30) in room 007 in the Bioinformatics Building. There we dont have a lot to discuss but feel free to join if you have any trouble with Python, Git or Gitlab. Also we are happy to answer any questions :)
-The Bioinformatics 2 Team |
Bioinformatics 2
This course builds on the Bioinformatics 1 lecture and the lectures are taught in English. While Bioinformatics 1 focuses on sequence-based bioinformatics methods, the Bioinformatics 2 lecture focuses on the bioinformatics theory and practice of molecular structures and interactions. Topics include:
- Protein structures
- Assignment and prediction of secondary structures
- Supervised machine learning
- Deep learning
- Homology modeling
- Molecular docking
- Drug sensitivity prediction
- Trustworthy AI
- Molecular representations
- Clustering
- QSAR
Requirements
- Mathematics for Computer Scientists 1 and 2
- Biostatistics Lab or Mathematics for Computer Scientists 3
- Programming 2
- Bioinformatics 1
In addition, knowledge of Python programming is required for exam admission (see the Exam Admission section). The first lecture will include an introduction to Python specifically aimed at participants who already know other programming languages (e.g., from Programming 2 and Bioinformatics 1) but cannot yet program in Python.
Lectures
Tuesday, 2:15–4:00 p.m., Building E2.1, Lecture Hall 007
Thursday, 2:15–4:00 p.m., Building E2.1, Lecture Hall 007
The first lecture will take place on Tuesday, April 7, 2026, in Building E2.1, Room 003 (aka the CIP Pool, directly to the left of the entrance).
On this day, we will not be holding a lecture in the traditional sense, but rather a Python crash course (see the Requirements section). Therefore, we ask that you bring your laptop if possible and install Python 3, conda, a text editor of your choice (e.g., VS Code), and Git beforehand. You will also need an account for the SIC GitLab to work on the programming projects. You must provide the corresponding username when registering for the course. If you can no longer find your SIC account credentials, you can reset your password here using your student email address.
Tutorials
Tutorials: Mondays 8:30–10:00 a.m., Building E2.1, Lecture Hall 007
Office Hours: Wednesday 2:00–4:00 p.m., Building E2.1, Lecture Hall 007
Exam Admission
To be eligible for the exam, each of the following conditions must be met:
- 50% score on the mini-tests
- No more than 2 mini-tests missed
- 50% score on the programming assignments
- No more than 2 programming assignment sheets not submitted
- Passing the regular code reviews
- Passing the challenge
More detailed information on this will be discussed again in the first lecture.
Exam Dates
Main Exam: 14.07.2026 2:00–4:00 p.m., Building E2.1, Lecture Hall 007
Re-exam: 29.09.2026 2:00–4:00 p.m., Building E1.3, Lecture Hall HS003
Requirements for Course Credit
Passing the exam or re-exam.
Course Registration
You must register for the course here in the CMS by April 14, 2026. If you missed the registration deadline but still wish to participate, please contact one of the teaching assistants via email. Registration in LSF is not required to participate. However, to take the exam, you must register for it in LSF no later than one week before the main exam or re-exam, respectively.